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Cytology‐based gene mutation tests to predict response to anti‐epidermal growth factor receptor therapy: A review

9 Nov 2010

Abstract excerpt

Recent therapeutic progresses in nonsmall cell lung cancer (NSCLC) and in colorectal cancer (CRC) are based on agents that specifically target the epidermal growth factor receptor (EGFR). To identify the patients most likely to benefit from such therapies, EGFR or KRAS gene mutation tests are mandatory, respectively, in NSCLC and in CRC. In patients with locally advanced or metastatic disease, exploiting...

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PMID: 21837660
DOI: 10.1002/dc.21512

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