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Article

Applications and limitations of oncogene mutation testing in clinical cytopathology.

Seminars in diagnostic pathology - 1 Nov 2013

Bellevicine Claudio, Vita Giulia De, Malapelle Umberto, Troncone Giancarlo

Abstract excerpt

In an increased number of settings, cytology represents the only source of sampling and it often substitutes histology as an independent diagnostic modality. Thus, DNA molecular targets to stratify patients for targeted therapy are often evaluated on cytology. In addition, DNA mutational tests may refine indeterminate thyroid and pancreas cytology. This review discusses the applications and limitations of DNA...

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PMID: 24342285
DOI: 10.1053/j.semdp.2013.11.008

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