Article
Comparative study of epidermal growth factor receptor mutation analysis on cytology smears and surgical pathology specimens from primary and metastatic lung carcinomas.
Cancer cytopathology - 1 Jul 2013
Khode Renu, Larsen Douglas A, Culbreath Brianne C, Parrish Shane, Walker Kimberly L, Sayage-Rabie Lubna, Beissner Robert S, Rao Arundhati
Abstract excerpt
BACKGROUND: The detection of epidermal growth factor receptor (EGFR) mutations on small biopsy or fine-needle aspiration samples is required to guide therapy in nonsmall cell lung cancer (NSCLC). In this study, the authors compared results from EGFR mutation testing on both cytologic smears and surgical specimens and also compared the performance of platforms using 2 different technologies (pyrosequencing and...
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