Article
Functional genetic variation at the NRGN gene and schizophrenia: evidence from a gene-based case-control study and gene expression analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2012
Ohi Kazutaka, Hashimoto Ryota, Yasuda Yuka, Fukumoto Motoyuki, Yamamori Hidenaga, Umeda-Yano Satomi, Okada Takeya, Kamino Kouzin, Morihara Takashi, Iwase Masao, Kazui Hiroaki, Numata Shusuke, Ikeda Masashi, Ohnuma Tohru, Iwata Nakao, Ueno Shu-ichi, Ozaki Norio, Ohmori Tetsuro, Arai Heii, Takeda Masatoshi
Abstract excerpt
Genome-wide association and follow-up studies have reported an association between schizophrenia and rs12807809 of the NRGN gene on chromosome 11q24.2. We investigated the association of five linkage disequilibrium-tagging SNPs and haplotypes that cover the NRGN gene with schizophrenia in a Japanese sample of 2,019 schizophrenia patients and 2,574 controls to determine whether rs12807809 is the most strongly...
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