Article
Genetic association between NRG1 and schizophrenia, major depressive disorder, bipolar disorder in Han Chinese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2016
Wen Zujia, Chen Jianhua, Khan Raja Amjad Waheed, Song Zhijian, Wang Meng, Li Zhiqiang, Shen Jiawei, Li Wenjin, Shi Yongyong
Abstract excerpt
Schizophrenia, major depressive disorder, and bipolar disorder are three major psychiatric disorders affecting around 0.66%, 3.3%, and 1.5% of the Han Chinese population respectively. Several genetic linkage analyses and genome wide association studies identified NRG1 as a susceptibility gene of schizophrenia, which was validated by its role in neurodevelopment, glutamate, and other neurotransmitter receptor...
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