Polymorphisms in NRGN are associated with schizophrenia, major depressive disorder and bipolar disorder in the Han Chinese population.

doi:10.1016/j.jad.2016.01.034

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Article

Polymorphisms in NRGN are associated with schizophrenia, major depressive disorder and bipolar disorder in the Han Chinese population.

Journal of affective disorders - 1 Apr 2016

Wen Zujia, Chen Jianhua, Khan Raja Amjad Waheed, Wang Meng, Song Zhijian, Li Zhiqiang, Shen Jiawei, Li Wenjin, Shi Yongyong

Abstract excerpt

BACKGROUND: The NRGN gene locates on 11q24 and encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. In a previous genome-wide association study of schizophrenia in the Caucasian population, rs12807809 of NRGN was found to be significantly associated with schizophrenia, moreover, it was further found to be associated with bipolar disorder. METHODS: We recruited 1248...

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PMID: 26828755
DOI: 10.1016/j.jad.2016.01.034

Genes

NRGN

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