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Genetic analysis of the NR2E1 gene as a candidate gene of schizophrenia.

Psychiatry research - 1 Nov 2020

Wang Yu-Yuan, Hsu Shih-Hsin, Tsai Hsin-Yao, Cheng Min-Chih

Abstract excerpt

NR2E1 is implicated in the regulation of neurogenesis and considered as a candidate gene for schizophrenia. We resequenced all the exons of NR2E1 in 547 patients with schizophrenia and 567 controls from Taiwan. We identified five common SNPs with no association with patients with schizophrenia. Further haplotype-based association analysis showed that two haplotypes within NR2E1 were correlated with the...

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PMID: 32805587
DOI: 10.1016/j.psychres.2020.113386

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