Article
Neuregulin 3 genetic variations and susceptibility to schizophrenia in a Chinese population.
Biological psychiatry - 15 Dec 2008
Wang Ying-Chieh, Chen Jen-Yeu, Chen Mao-Liang, Chen Chia-Hsiang, Lai I-Ching, Chen Tzu-Ting, Hong Chen-Jee, Tsai Shih-Jen, Liou Ying-Jay
Abstract excerpt
BACKGROUND: The study investigated the possible association of NRG3 gene and schizophrenia in a Han Chinese population. METHODS: Of a total of 1345, 270 unrelated schizophrenia inpatients, 235 normal control subjects, and 280 nuclear families (trios) with schizophrenia probands were studied. Nine single nucleotide polymorphisms (SNPs) spanning intron 1 to exon 9 of the NRG3 gene were analyzed, starting with the...
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