Article
Supportive evidence for neuregulin 1 as a susceptibility gene for schizophrenia in a Japanese population.
Neuroscience letters - 27 Mar 2006
Fukui Naoki, Muratake Tatsuyuki, Kaneko Naoshi, Amagane Hideki, Someya Toshiyuki
Abstract excerpt
Schizophrenia is a complex genetic disorder and affects approximately 1% of the population worldwide. Recently, Stefansson et al. identified neuregulin 1 (NRG1) on 8p12 as a susceptibility gene for schizophrenia in the Icelandic population. It was reported that the at-risk haplotype ("Hapice") constructed from five SNPs and two microsatellite markers was found to be over-represented in patients with schizophrenia...
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