Article
A systematic study of gene expression variation at single-nucleotide resolution reveals widespread regulatory roles for uAUGs.
Genome research - 1 Jun 2012
Yun Yue, Adesanya T M Ayodele, Mitra Robi D
Abstract excerpt
Regulatory single-nucleotide polymorphisms (rSNPs) alter gene expression. Common approaches for identifying rSNPs focus on sequence variants in conserved regions; however, it is unknown what fraction of rSNPs is undetectable using this approach. We present a systematic analysis of gene expression variation at the single-nucleotide level in the Saccharomyces cerevisiae GAL1-10 regulatory region. We exhaustively...
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