Article

DNA variants affecting the expression of numerous genes in <i>trans</i> have diverse mechanisms of action and evolutionary histories

2019-08-19

Abstract excerpt

DNA variants that alter gene expression contribute to variation in many phenotypic traits. In particular, trans -acting variants, which are often located on different chromosomes from the genes they affect, are an important source of heritable gene expression variation. However, our knowledge about the identity and mechanism of causal trans -acting variants remains limited. Here, we developed a fine-mapping stra...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 04564f1a-2323-55cc-89b9-f38f8d4d8440
DOI: 10.1101/740076

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA variants affecting the expression of numerous genes in <i>trans</i> have diverse mechanisms of action and evolutionary historiesDOI 10.1101/740076Read

DNA variants affecting the expression of numerous genes in trans have diverse mechanisms of action and evolutionary histories.Semantic proximity Read

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross.Semantic proximity Read

Multiple epistatic DNA variants in a single gene affect gene expression in trans.Semantic proximity Read

Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae.Semantic proximity Read

High-resolution mapping of cis-regulatory variation in budding yeastSemantic proximity Read

A trans-acting Variant within the Transcription Factor RIM101 Interacts with Genetic Background to Determine its Regulatory Capacity.Semantic proximity Read

Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variation.Semantic proximity Read

High-resolution mapping of cis-regulatory variation in budding yeast.Semantic proximity Read

Genetics of <i>trans</i> -regulatory variation in gene expressionSemantic proximity Read

The molecular mechanism of a cis-regulatory adaptation in yeast.Semantic proximity Read

Natural gene expression variation studies in yeast.Semantic proximity Read

Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast.Semantic proximity Read