Article
High-resolution mapping of cis-regulatory variation in budding yeast.
Proceedings of the National Academy of Sciences of the United States of America - 12 Dec 2017
Kita Ryosuke, Venkataram Sandeep, Zhou Yiqi, Fraser Hunter B
Abstract excerpt
Genetic variants affecting gene-expression levels are a major source of phenotypic variation. The approximate locations of these variants can be mapped as expression quantitative trait loci (eQTLs); however, a major limitation of eQTLs is their low resolution, which precludes investigation of the causal variants and their molecular mechanisms. Here we report RNA-seq and full genome sequences for 85 diverse...
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