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Article

The C-terminus of kinesin-14 Ncd is a crucial component of the force generating mechanism.

FEBS letters - 23 Mar 2012

Szczęsna Ewa, Kasprzak Andrzej A

Abstract excerpt

Ncd, a member of kinesin-14 family motors, uses the power stroke, a lever-like pivoting action of a long and stiff element, to exert force and generate movement. To better understand the role of the Ncd C-terminus in this process we produced four Ncd mutants in which this segment was altered or deleted. For these proteins we measured their affinity to the microtubule, steady-state ATPase and gliding velocity in...

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Source

Identifiers

PMID: 22449971
DOI: 10.1016/j.febslet.2012.02.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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