Spatial relationship between heads of dimeric Ncd in the presence of nucleotides and microtubules.

Abstract excerpt

Kinesins are molecular motors that produce mechanical work at the expense of ATP hydrolysis. Here, we studied Ncd (non-claret disjunctional), a (-)-end-directed member of this superfamily. To gain insight into the mechanism by which Ncd generates force and movement, we measured distances between the heads in dimeric Ncd-250-700 using fluorescence resonance energy transfer (FRET). About 5% of Ncd heads were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Dimerization
• Share to Drosophila Proteins
• Share to Fluorescence Resonance Energy Transfer