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Article

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis.

Science (New York, N.Y.) - 21 Mar 1997

Boyartchuk V L, Ashby M N, Rine J

Abstract excerpt

Prenylated proteins contain a covalently linked cholesterol intermediate near their carboxyl-termini. Maturation of most prenylated proteins involves proteolytic removal of the last three amino acids. Two genes in Saccharomyces cerevisiae, RCE1 and AFC1, were identified that appear to be responsible for this processing. The Afc1 protein is a zinc protease that participates in the processing of yeast a-factor...

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Source

Identifiers

PMID: 9065405
DOI: 10.1126/science.275.5307.1796

Genes

RCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Modulation of Ras and a-factor function by carboxyl-terminal proteolysis.PMID 9065405Read ↗

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