Article
The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities.
Molecular and cellular biology - 1 Jun 2000
Trueblood C E, Boyartchuk V L, Picologlou E A, Rozema D, Poulter C D, Rine J
Abstract excerpt
Many proteins that contain a carboxyl-terminal CaaX sequence motif, including Ras and yeast a-factor, undergo a series of sequential posttranslational processing steps. Following the initial prenylation of the cysteine, the three C-terminal amino acids are proteolytically removed, and the newly formed prenylcysteine is carboxymethylated. The specific amino acids that comprise the CaaX sequence influence whether...
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