Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function.

Human brain mapping - 1 Sept 2013

Pauli Andreina, Prata Diana P, Mechelli Andrea, Picchioni Marco, Fu Cynthia H Y, Chaddock Christopher A, Kane Fergus, Kalidindi Sridevi, McDonald Colm, Kravariti Eugenia, Toulopoulou Timothea, Bramon Elvira, Walshe Muriel, Ehlert Natascha, Georgiades Anna, Murray Robin, Collier David A, McGuire Philip

Abstract excerpt

The genes for the dopamine transporter (DAT) and the D-Amino acid oxidase activator (DAOA or G72) have been independently implicated in the risk for schizophrenia and in bipolar disorder and/or their related intermediate phenotypes. DAT and G72 respectively modulate central dopamine and glutamate transmission, the two systems most robustly implicated in these disorders. Contemporary studies have demonstrated that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Dopamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

Share to Healthy Volunteers

Share to Image Processing, Computer-Assisted

Share to Psychotic Disorders

Share to Synaptic Transmission

Share to Verbal Learning

Source

Open in PubMed Open full text

Identifiers

PMID: 22438288
DOI: 10.1002/hbm.22061
PMCID: PMC6869864

Genes

DAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function.PMID 22438288Read ↗

Genetic vulnerability to psychosis and cortical function: epistatic effects between DAAO and G72.Semantic proximity Read ↗

Effect of D-amino acid oxidase activator (DAOA; G72) on brain function during verbal fluency.Semantic proximity Read ↗

Genetic variation in G72 correlates with brain activation in the right middle temporal gyrus in a verbal fluency task in healthy individuals.Semantic proximity Read ↗

A combined study of genetic association and brain imaging on the DAOA gene in schizophrenia.Semantic proximity Read ↗

Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia.Semantic proximity Read ↗

Epistasis between the DAT 3' UTR VNTR and the COMT Val158Met SNP on cortical function in healthy subjects and patients with schizophrenia.Semantic proximity Read ↗

The G72/G30 gene complex and cognitive abnormalities in schizophrenia.Semantic proximity Read ↗

Differential effects of DAAO on regional activation and functional connectivity in schizophrenia, bipolar disorder and controls.Semantic proximity Read ↗

COMT rs4680 and DAOA rs947267 Polymorphism Interact to Influence Cognition and Psychiatric Symptoms in Chronic Schizophrenia.Semantic proximity Read ↗

Interactive effects of DAOA (G72) and catechol-O-methyltransferase on neurophysiology in prefrontal cortex.Semantic proximity Read ↗

Glutamate and psychosis risk.Semantic proximity Read ↗

Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.