Article
Differential effects of DAAO on regional activation and functional connectivity in schizophrenia, bipolar disorder and controls.
NeuroImage - 15 Jun 2011
Papagni Sergio Alessandro, Mechelli Andrea, Prata Diana P, Kambeitz Joseph, Fu Cynthia H Y, Picchioni Marco, Walshe Muriel, Toulopoulou Timothea, Bramon Elvira, Murray Robin M, Collier David A, Bellomo Antonello, McGuire Philip
Abstract excerpt
Recent studies have identified DAAO as a probable susceptibility gene for schizophrenia and bipolar disorder. However, little is known about how this gene affects brain function to increase vulnerability to these disorders. We examined the impact of DAAO genotype (rs3918346) on brain function in patients with schizophrenia, patients with bipolar I disorder and healthy controls. We tested the hypothesis that a...
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