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Article

Glutamate and psychosis risk.

Current pharmaceutical design - 1 Jan 2012

Egerton Alice, Fusar-Poli Paolo, Stone James M

Abstract excerpt

Increasing evidence suggests that abnormalities in glutamatergic transmission may be associated with psychosis risk. Genetic polymorphisms associated with schizophrenia converge on NMDA receptor signalling pathways, and transgenic animal models and human neuroimaging studies have shown the functional impact of these risk alleles. Animal models have also shown that environmental risk factors, such as stress,...

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Identifiers

PMID: 22239577
DOI: 10.2174/138161212799316244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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