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Article

Effect of D-amino acid oxidase activator (DAOA; G72) on brain function during verbal fluency.

Human brain mapping - 1 Jan 2012

Prata Diana P, Papagni Sergio A, Mechelli Andrea, Fu Cynthia H Y, Kambeitz Joseph, Picchioni Marco, Kane Fergus, Kalidindi Sridevi, McDonald Colm, Kravariti Eugenia, Toulopoulou Timothea, Bramon Elvira, Walshe Muriel, Murray Robin, Collier David A, McGuire Philip K

Abstract excerpt

BACKGROUND: The D-Amino acid oxidase activator (G72 or DAOA) is believed to play a key role in the regulation of central glutamatergic transmission which is seen to be altered in psychosis. It is thought to regulate D-amino acid oxidase (DAO), which metabolizes D-serine, a co-agonist of NMDA-type glutamate receptors and to be involved in dendritic arborization. Linkage, genetic association and expression studies...

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Identifiers

PMID: 21391259
DOI: 10.1002/hbm.21198
PMCID: PMC6870192

Genes

DAOA
DAO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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