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Article

Acetylcholinesterase inhibition ameliorates deficits in motivational drive.

Behavioral and brain functions : BBF - 20 Mar 2012

Martinowich Keri, Cardinale Kathleen M, Schloesser Robert J, Hsu Michael, Greig Nigel H, Manji Husseini K

Abstract excerpt

BACKGROUND: Apathy is frequently observed in numerous neurological disorders, including Alzheimer's and Parkinson's, as well as neuropsychiatric disorders including schizophrenia. Apathy is defined as a lack of motivation characterized by diminished goal-oriented behavior and self-initiated activ...

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Identifiers

PMID: 22433906
DOI: 10.1186/1744-9081-8-15
PMCID: PMC3328273

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22433906-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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