Article

Conditioned versus innate effort-based tasks reveal divergence in antidepressant effect on motivational state in male mice

2025-02-08

Abstract excerpt

Antidepressant-induced apathy syndrome is reported in a high number of patients. It is characterised by loss of motivation for daily activities and emotional blunting. It has a negative impact on quality of life and treatment outcome, yet the changes in underlying neurobiology driving this syndrome remain unclear. To begin to address this, a comprehensive understanding of how different classes of antidepressant tr...

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Literature Corpus work: bc701cd1-7cc4-592c-a06a-404a73c651e0
DOI: 10.1101/2025.02.04.636449

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