Article
Motor and anxiety effects of PNU-282987, an alpha7 nicotinic receptor agonist, and stress in an animal model of Alzheimer's disease.
Current Alzheimer research - 1 Jun 2013
Vicens Paloma, Ribes Diana, Heredia Luis, Torrente Margarita, Domingo José L
Abstract excerpt
Behavioral and Psychological Symptoms in Dementia (BPSD) are also seen in Alzheimer's disease (AD), being agitation and anxiety common symptoms. Since cholinergic agonists used to be the first pharmacological intervention in AD and this neurotransmission system have been related to cognitive and behavioral symptoms in this serious disease, we here address the question of a possible therapeutic role of PNU-282987...
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