The interleukin 28B rs12979860 C/T polymorphism and serum cholesterol as predictors of fibrosis progression in patients with chronic hepatitis C and persistently normal transaminases.

doi:10.1002/jmv.23259

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Article

The interleukin 28B rs12979860 C/T polymorphism and serum cholesterol as predictors of fibrosis progression in patients with chronic hepatitis C and persistently normal transaminases.

Journal of medical virology - 1 May 2012

Fabris Carlo, Falleti Edmondo, Cussigh Annarosa, Bitetto Davide, Fontanini Elisabetta, Colletta Cosimo, Vandelli Carmen, Cmet Sara, Ceriani Elisa, Smirne Carlo, Toniutto Pierluigi, Pirisi Mario

Abstract excerpt

The interleukin 28B (IL-28B) rs12979860 C/T polymorphism is a predictor of spontaneous and treatment-induced hepatitis C virus (HCV) clearance. The C/C genotype is associated with higher serum cholesterol, predictor of a favorable outcome in chronic hepatitis C. Whether IL-28B polymorphism and serum cholesterol play a role in modulating the history of mild hepatitis C is unknown. To clarify this issue, 93...

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PMID: 22431022
DOI: 10.1002/jmv.23259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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