Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17‐mediated autoimmunity in the CNS

20 Mar 2012

Abstract excerpt

Different viruses trigger pattern recognition receptor systems, such as Toll-like receptors or cytosolic RIG-I like helicases (RLH), and thus induce early type I interferon (IFN-I) responses. Such responses may confer protection until adaptive immunity is activated to an extent that the pathogen can be eradicated. Interestingly, the same innate immune mechanisms that are relevant for early pathogen defense have a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22430251
DOI: 10.1038/icb.2012.8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17‐mediated autoimmunity in the CNSPMID 22430251Read ↗

Type I interferon pathway in CNS homeostasis and neurological disordersSemantic proximity Read ↗

RIG-I-Like Receptors and Type I Interferonopathies.Semantic proximity Read ↗

RIG-I-like receptors and autoimmune diseases.Semantic proximity Read ↗

Type III Interferons: Emerging Roles in AutoimmunitySemantic proximity Read ↗

Targeting interferon- <sub>λ</sub> signaling promotes recovery from central nervous system autoimmunitySemantic proximity Read ↗

TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITYSemantic proximity Read ↗

Type I Interferons Are Essential in Controlling Neurotropic Coronavirus Infection Irrespective of Functional CD8 T CellsSemantic proximity Read ↗

Targeting IFN-λ Signaling Promotes Recovery from Central Nervous System AutoimmunitySemantic proximity Read ↗

Human life within a narrow range: The lethal ups and downs of type I interferonsSemantic proximity Read ↗

IL ‐17: A new actor in IFN ‐driven systemic autoimmune diseasesSemantic proximity Read ↗

Does type-I interferon drive systemic autoimmunity?Semantic proximity Read ↗

Toll-Like Receptors as Interferon-Regulated Genes and Their Role in DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.