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Article

Does type-I interferon drive systemic autoimmunity?

Autoimmunity reviews - 1 Sept 2017

Picard Cécile, Belot Alexandre

Abstract excerpt

Type-I interferon (IFN)-mediated immune response involves both innate and adaptive immune system and has a pivotal role in antiviral defence. A complex interplay of intracellular signaling pathways and tight regulatory systems drive the IFN activation. The observation of an aberrant stimulation of this system as a common molecular basis in peculiar inherited autoimmune and autoinflammatory disorders led to the...

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Identifiers

PMID: 28694138
DOI: 10.1016/j.autrev.2017.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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