Article
Natural product biosynthetic gene diversity in geographically distinct soil microbiomes.
Applied and environmental microbiology - 1 May 2012
Reddy Boojala Vijay B, Kallifidas Dimitris, Kim Jeffrey H, Charlop-Powers Zachary, Feng Zhiyang, Brady Sean F
Abstract excerpt
The number of bacterial species estimated to exist on Earth has increased dramatically in recent years. This newly recognized species diversity has raised the possibility that bacterial natural product biosynthetic diversity has also been significantly underestimated by previous culture-based studies. Here, we compare 454-pyrosequenced nonribosomal peptide adenylation domain, type I polyketide ketosynthase...
Topics
- Bacteria
- Biodiversity
- Biological Products
- Biosynthetic Pathways
- Genetic Variation
- Geography
- Metagenome
- Polyketide Synthases
- Soil Microbiology