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Article

Chemical-biogeographic survey of secondary metabolism in soil.

Proceedings of the National Academy of Sciences of the United States of America - 11 Mar 2014

Charlop-Powers Zachary, Owen Jeremy G, Reddy Boojala Vijay B, Ternei Melinda A, Brady Sean F

Abstract excerpt

In this study, we compare biosynthetic gene richness and diversity of 96 soil microbiomes from diverse environments found throughout the southwestern and northeastern regions of the United States. The 454-pyroseqencing of nonribosomal peptide adenylation (AD) and polyketide ketosynthase (KS) domain fragments amplified from these microbiomes provide a means to evaluate the variation of secondary metabolite...

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Identifiers

PMID: 24550451
DOI: 10.1073/pnas.1318021111
PMCID: PMC3956145

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Source receipt: pubmed, retrieved 7 Sept 2026.

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