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Article

ZEN-4/MKLP1 is required to polarize the foregut epithelium.

Current biology : CB - 8 Jun 2004

Portereiko Michael F, Saam Jennifer, Mango Susan E

Abstract excerpt

BACKGROUND: Epithelial tubes are a key component of organs and are generated from cells with distinct apico-basolateral polarity. Here, we describe a novel function during tubulogenesis for ZEN-4, the Caenorhabditis elegans ortholog of mitotic kinesin-like protein 1 (MKLP1), and CYK-4, which contains a RhoGAP (GTPase-activating protein) domain. Previous studies revealed that these proteins comprise...

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Source

Identifiers

PMID: 15182666
DOI: 10.1016/j.cub.2004.05.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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