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Article

DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.

Cortex; a journal devoted to the study of the nervous system and behavior - 1 Mar 2013

Peciña Marta, Mickey Brian J, Love Tiffany, Wang Heng, Langenecker Scott A, Hodgkinson Colin, Shen Pei-Hong, Villafuerte Sandra, Hsu David, Weisenbach Sara L, Stohler Christian S, Goldman David, Zubieta Jon-Kar

Abstract excerpt

Dopamine (DA) neurotransmission through D2 receptors (DRD2) has been implicated in the regulation of reward processing, cognition and the effects of drugs of abuse, and also has significant effects in responses to stressors and salient aversive stimuli. An examination of the influence of genetic variation across multiple psychophysical measures therefore appears critical to understand the neurobiology of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22424959
DOI: 10.1016/j.cortex.2012.01.010
PMCID: PMC3381848

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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