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Article

Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2011

Nikolova Yuliya S, Ferrell Robert E, Manuck Stephen B, Hariri Ahmad R

Abstract excerpt

Research integrating neuroimaging and molecular genetics has yielded important insights into how variability in brain chemistry predicts individual differences in brain function, behavior and related risk for psychopathology. However, existing studies have been limited by their focus on the independent effects of single polymorphisms with modest impact on brain chemistry. Here, we explored the effects of five...

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Identifiers

PMID: 21593733
DOI: 10.1038/npp.2011.82
PMCID: PMC3154113

Genes

DRD2
COMT
DRD4

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