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Article

Association between a promoter dopamine D2 receptor gene variant and the personality trait detachment.

Biological psychiatry - 1 Apr 2003

Jönsson Erik G, Cichon Sven, Gustavsson J Petter, Grünhage Frank, Forslund Kaj, Mattila-Evenden Marja, Rylander Gunnar, Asberg Marie, Farde Lars, Propping Peter, Nöthen Markus M

Abstract excerpt

BACKGROUND: Personality traits have shown considerable heritable components. Striatal dopamine D(2) receptor density, as determined by positron-emission tomography, has been associated with detached personality, as assessed by the Karolinska Scales of Personality. A putative functional promoter polymorphism in the dopamine D(2) receptor gene (DRD2), -141C ins/del, has been associated with dopamine D(2) receptor...

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Share to DRD2 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Personality Disorders

Share to Promoter Regions, Genetic

Share to Receptors, Dopamine D2

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Share to Tomography, Emission-Computed

Source

Identifiers

PMID: 12679235
DOI: 10.1016/s0006-3223(02)01732-8

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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