Article
Reduced connexin40 protein expression in the right atrial appendage of patients bearing the minor connexin40 allele (-44 G --> A).
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Aug 2012
Chaldoupi Sevasti-Maria, Hubens Lisette E G, Smit Duijzentkunst Daan A, van Stuijvenberg Leonie, Bierhuizen Marti F A, van Aarnhem Egidius E H L, Nelen Marcel, de Bakker Jacques M T, Hauer Richard N W, van Rijen Harold V M, Loh Peter, van Veen Toon A B
Abstract excerpt
AIMS: The occurrence of connexin40 (Cx40) minor polymorphism (-44 G → A) was increased in patients with idiopathic atrial fibrillation (AF), although its effect on atrial Cx40 protein expression is unknown. We aimed to evaluate whether alterations in Cx40 are directly linked to the development of AF, we studied the effect of this polymorphism on Cx40 expression and distribution in patients without any history of...
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