Article
The association of human connexin 40 genetic polymorphisms with atrial fibrillation.
International journal of cardiology - 2 Mar 2007
Juang Jyh-Ming, Chern Yi-Rong, Tsai Chia-Ti, Chiang Fu-Tien, Lin Jiunn-Lee, Hwang Juey-Jen, Hsu Kwan-Li, Tseng Chuen-Den, Tseng Yung-Zu, Lai Ling-Ping
Abstract excerpt
BACKGROUND: There is evidence showing that genetic factors contribute to the pathogenesis of atrial fibrillation (Af). We investigated the association between Af and polymorphisms of the connexin 40 (Cx40) gene, which is important in the electrical coupling between atrial myocytes. METHODS: We performed an association study between two Cx40 single nucleotide polymorphisms (SNPs) (Cx40 -44 and +71 allele) and Af....
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