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Article

Low prevalence of connexin-40 gene variants in atrial tissues and blood from atrial fibrillation subjects.

BMC medical genetics - 7 Nov 2012

Tchou Gregory D, Wirka Robert C, Van Wagoner David R, Barnard John, Chung Mina K, Smith Jonathan D

Abstract excerpt

BACKGROUND: The atrial gap junction protein connexin-40 (Cx40) has been implicated to play an important role in atrial conduction and development of atrial fibrillation (AF). However, the frequency of Cx40 mutations in AF populations and their impact on Cx40 expression remains unclear. In this study, we sought to identify polymorphisms in the Cx40 gene GJA5, investigate the potential functional role of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23134779
DOI: 10.1186/1471-2350-13-102
PMCID: PMC3507864

Genes

GJA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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