Article
The role of connexin40 in atrial fibrillation.
Cardiovascular research - 1 Oct 2009
Chaldoupi Sevasti-Maria, Loh Peter, Hauer Richard N W, de Bakker Jacques M T, van Rijen Harold V M
Abstract excerpt
Connexin40 (Cx40) is a major gap-junction protein in the atrial myocardium. In the heart, gap junctions are responsible for cell-to-cell conduction of the action potential. In several cardiac diseases, the expression of connexins is changed and is associated with increased propensity for arrhythmias. Atrial fibrillation (AF) is the most common arrhythmia in man with a diverse clinical presentation, different...
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