Article
Absence of connexin 40 gene polymorphism, as a marker of undetected atrial fibrillation in patients with unexplained cerebral ischemic events.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology - 1 Oct 2009
Chaldoupi Sevasti-Maria, Soedamah-Muthu Sabita S, Regieli Jakub, Werf Christian van de, Nelen Marcel, van der Smagt Jasper J, Algra Ale, Hauer Richard N W, Doevendans Pieter A, Loh Peter
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is a major cause of cerebral infarction. Idiopathic AF is strongly associated with the human minor connexin 40 (Cx40) promotor polymorphism. We examined the prevalence of the minor Cx40 allele in patients with cerebral ischemia and no other cardiovascular disease (CVD), as an indication of underlying idiopathic AF. METHODS: In patients with cerebral ischemia without prior CVD...
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