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Article

Fine mapping study reveals novel candidate genes for carotid intima-media thickness in Dominican Republican families.

Circulation. Cardiovascular genetics - 1 Apr 2012

Wang Liyong, Beecham Ashley, Zhuo Degen, Dong Chuanhui, Blanton Susan H, Rundek Tatjana, Sacco Ralph L

Abstract excerpt

BACKGROUND: Carotid intima-media thickness (CIMT) is a subclinical measure for atherosclerosis. Previously, we have mapped quantitative trait loci (QTLs) for CIMT to chromosomes 7p (maximum logarithm of odds=3.1) and to 14q (maximum logarithm of odds=2.3). We sought to identify the underlying genetic variants within those QTLs. METHODS AND RESULTS: Using the 100 extended Dominican Republican (DR) families...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22423143
DOI: 10.1161/CIRCGENETICS.111.961763
PMCID: PMC3341091

Genes

ANLN
AOAH
FOXN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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