Article
Follow-up association study of linkage regions reveals multiple candidate genes for carotid plaque in Dominicans.
Atherosclerosis - 1 Jul 2012
Dong Chuanhui, Beecham Ashley, Wang Liyong, Blanton Susan H, Rundek Tatjana, Sacco Ralph L
Abstract excerpt
OBJECTIVE: Carotid plaque is a marker of subclinical atherosclerosis with a genetic component. The aim of this follow-up fine mapping study was to identify candidate genes for carotid plaque within four linkage regions. METHODS: We successfully genotyped 3712 single nucleotide polymorphisms (SNPs) under the four linkage regions that were previously identified in 100 extended Dominican families. Family-based...
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