Back to search

Article

Genetic associations with carotid intima-media thickness link to atherosclerosis biology with sex-differences in sub-Saharan Africans

2021-01-22

Abstract excerpt

<title>Abstract</title> <p>Atherosclerosis precedes the onset of many clinical manifestations of cardiovascular diseases (CVDs). We used carotid intima-media thickness (cIMT) to investigate genetic susceptibility to atherosclerosis in 7894 unrelated adults (3963 women, 3931 men) aged 40 to 60 years resident in four sub-Saharan African countries. cIMT was measured by ultrasound and genotyping was performed on the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fb8b659c-9901-5d72-990e-8b6bda171af9
DOI
10.21203/rs.3.rs-147838/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic associations with carotid intima-media thickness link to atherosclerosis biology with sex-differences in sub-Saharan AfricansDOI 10.21203/rs.3.rs-147838/v1
Genetic associations with carotid intima-media thickness link to atherosclerosis with sex-specific effects in sub-Saharan Africans.Semantic proximity
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thicknessSemantic proximity
Integrative observational and genetic evidence from the UK Biobank supports carotid intima-media thickness as a window into cardiac remodelingSemantic proximity
Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.Semantic proximity
Carotid intima-media thickness in UK Biobank: Identification of novel genome-wide loci, sex-specific effects and genetic correlations with obesity and glucometabolic traitsSemantic proximity
Epigenome-Wide Association Study in Asian Cohort Identifies Novel DNA Methylation Markers for Carotid Intima-Media ThicknessSemantic proximity
Epigenome-Wide Association Study in Asian Cohort Identifies Novel DNA Methylation Markers for Carotid Intima-Media ThicknessSemantic proximity
Integrative Observational and Genetic Evidence From the UK Biobank Supports Carotid Intima-Media Thickness as a Window Into Cardiac Remodeling.Semantic proximity
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomesSemantic proximity
Phenotypic and genetic effect of carotid intima-media thickness on the risk of stroke.Semantic proximity
Fine mapping study reveals novel candidate genes for carotid intima-media thickness in Dominican Republican families.Semantic proximity
Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank.Semantic proximity
Select a neighboring publication to make it the new centre.