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Article

Rare variants in previously identified linkage regions associated with carotid plaque in Dominican Republic families.

PloS one - 1 Jan 2000

Dueker Nicole D, Beecham Ashley, Wang Liyong, Dong Chuanhui, Sacco Ralph L, Blanton Susan H, Rundek Tatjana

Abstract excerpt

Carotid plaque is a subclinical measure of atherosclerosis. We have previously shown measures of carotid plaque to be heritable in a sample of 100 Dominican families and found evidence for linkage and association of common variants (CVs) on 7q36, 11p15, 14q32 and 15q23 with plaque presence. Our current study aimed to refine these regions further and identify rare variants (RVs) influencing plaque presence....

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Identifiers

PMID: 35020748
DOI: 10.1371/journal.pone.0250799
PMCID: PMC8754284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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