Article
A genome-wide scan for carotid artery intima-media thickness: the Mexican-American Coronary Artery Disease family study.
Stroke - 1 Mar 2005
Wang Dai, Yang Huiying, Quiñones Manuel J, Bulnes-Enriquez Isabel, Jimenez Xochitl, De La Rosa Roxana, Modilevsky Tamara, Yu Katherine, Li Yanjie, Taylor Kent D, Hsueh Willa A, Hodis Howard N, Rotter Jerome I
Abstract excerpt
BACKGROUND AND PURPOSE: Carotid artery intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with coronary artery disease (CAD), and stroke. CIMT is also an important predictor of clinical cardiovascular events. To systematically identify the genetic determinants of CIMT, we performed a genome-wide scan using data from 91 2-generation Mexican American families ascertained via a...
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