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Article

Sequencing of candidate genes in Dominican families implicates both rare exonic and common non-exonic variants for carotid intima-media thickness at bifurcation.

Human genetics - 1 Oct 2015

Wang Liyong, Beecham Ashley, Dueker Nicole, Blanton Susan H, Rundek Tatjana, Sacco Ralph L

Abstract excerpt

Through linkage and tagSNP-based association studies in 100 Dominican Republic (DR) families, we previously identified ANLN and AOAH (7p14.3) as candidate genes for carotid intima-media thickness at bifurcation (bIMT). Introns, exons, and flanking regions of ANLN and AOAH were re-sequenced in 151 individuals from nine families with evidence for linkage at 7p14.3. For common variants [CV, minor allele frequency...

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Share to Carboxylic Ester Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26319989
DOI: 10.1007/s00439-015-1592-z
PMCID: PMC4570583

Genes

ANLN
AOAH
MAF

Provenance

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