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Article

Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2022

Yeung Ming Wai, Wang Siqi, van de Vegte Yordi J, Borisov Oleg, van Setten Jessica, Snieder Harold, Verweij Niek, Said M Abdullah, van der Harst Pim

Abstract excerpt

OBJECTIVE: Carotid artery intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. Twenty susceptibility loci for cIMT were previously identified and the identification of additional susceptibility loci furthers our knowledge on the genetic architecture underlying atherosclerosis. APPROACH AND RESULTS: We performed 3 genome-wide association studies in 45 185 participants from the...

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Identifiers

PMID: 34852643
DOI: 10.1161/ATVBAHA.121.317007
PMCID: PMC8939707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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