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Article

5-HTTLPR S-allele: a genetic plasticity factor regarding the effects of life events on personality?

Genes, brain, and behavior - 1 Aug 2012

Kuepper Y, Wielpuetz C, Alexander N, Mueller E, Grant P, Hennig J

Abstract excerpt

The S-allele of the 5-HTTLPR has been identified as a genetic vulnerability factor, being associated with an increased risk for affective disorders and/or maladaptive traits (e.g. neuroticism), especially after exposition to negative life-events (LEs). Alternatively, it has been hypothesized that this genetic risk factor might constitute a genetic plasticity factor. That is, S-allele carriers are not only...

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Identifiers

PMID: 22420614
DOI: 10.1111/j.1601-183X.2012.00783.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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