Article
Variations in 5-HTTLPR: relation to familiar risk of affective disorder, life events, neuroticism and cortisol.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Feb 2010
Vinberg Maj, Mellerup Erling, Andersen Per Kragh, Bennike Bente, Kessing Lars Vedel
Abstract excerpt
BACKGROUND: Variations in the serotonin transporter gene (5-HTTLPR) and stressful life events are associated with affective disorders. AIM: To investigate whether the distribution of the alleles of the 5-HTTLPR is associated with a genetic predisposition to affective disorder and whether these variations interact with life events in relation to depressive symptoms, neuroticism and salivary cortisol. METHOD: In a...
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