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Article

5-HTTLPR moderates effects of current life events on neuroticism: differential susceptibility to environmental influences.

Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010

Pluess Michael, Belsky Jay, Way Baldwin M, Taylor Shelley E

Abstract excerpt

Research chronicling links between a polymorphism in the serotonin-transporter gene (5-HTTLPR) and neuroticism has yielded inconsistent results. One possible explanation for this inconsistency is that any gene-phenotype association is obscured by a gene-X-environment (GXE) interaction. We studied a healthy non-clinical sample (N=118) to determine whether the 5-HTTLPR interacts with current life events in...

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Identifiers

PMID: 20573579
DOI: 10.1016/j.pnpbp.2010.05.028
PMCID: PMC2915757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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