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Article

Interaction between the 5-HTTLPR genotype, impact of stressful life events, and trait neuroticism on depressive symptoms in healthy volunteers.

Psychiatric genetics - 1 Jun 2013

Markus C Rob

Abstract excerpt

INTRODUCTION: Recent biopsychological research on stress-related psychopathology shows promising evidence for the 5-hydroxytryptamine (5-HT) transporter linked polymorphic region (5-HTTLPR) genotype by life event interaction on depression. Yet, there appears to be variability in replicating such findings. From leading cognitive models of depression, it can be deduced that mainly high-impact events, particularly...

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PMID: 23492930
DOI: 10.1097/YPG.0b013e32835fe3e1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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