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Article

Role of the gut endoderm in relaying left-right patterning in mice.

PLoS biology - 1 Jan 2012

Viotti Manuel, Niu Lei, Shi Song-Hai, Hadjantonakis Anna-Katerina

Abstract excerpt

Establishment of left-right (LR) asymmetry occurs after gastrulation commences and utilizes a conserved cascade of events. In the mouse, LR symmetry is broken at a midline structure, the node, and involves signal relay to the lateral plate, where it results in asymmetric organ morphogenesis. How information transmits from the node to the distantly situated lateral plate remains unclear. Noting that embryos...

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Identifiers

PMID: 22412348
DOI: 10.1371/journal.pbio.1001276
PMCID: PMC3295824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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