Article
Establishment of left-right asymmetry in vertebrate development: the node in mouse embryos.
Cellular and molecular life sciences : CMLS - 1 Dec 2013
Komatsu Yoshihiro, Mishina Yuji
Abstract excerpt
Establishment of vertebrate left-right asymmetry is a critical process for normal embryonic development. After the discovery of genes expressed asymmetrically along the left-right axis in chick embryos in the mid 1990s, the molecular mechanisms responsible for left-right patterning in vertebrate embryos have been studied extensively. In this review article, we discuss the mechanisms by which the initial symmetry...
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